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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CDK5R2 All Species: 8.79
Human Site: S334 Identified Species: 21.48
UniProt: Q13319 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q13319 NP_003927.1 367 38705 S334 N E G E A A A S G G G P P S G
Chimpanzee Pan troglodytes XP_516099 367 38658 S334 N E G E A A A S G G G P P S G
Rhesus Macaque Macaca mulatta XP_001113074 307 34072 I275 M S S K M L Q I N A D P H Y F
Dog Lupus familis XP_853120 458 47635 G422 N E G E A A A G A G G P P S G
Cat Felis silvestris
Mouse Mus musculus O35926 369 38896 S334 N E G E A A A S T G G P P S G
Rat Rattus norvegicus P61810 307 34013 I275 M S S K M L Q I N A D P H Y F
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis NP_001089375 320 35634 N288 S A K M L Q I N S D P H F F T
Zebra Danio Brachydanio rerio NP_001017569 308 34577 I275 M S A K M L Q I N S D P H F F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22695 356 39856 A323 T F W N R C V A M V T S H S R
Sea Urchin Strong. purpuratus XP_794538 375 41683 R340 D K D R F W S R C I K I I N S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 49.5 77.2 N.A. 94.3 48.7 N.A. N.A. N.A. 58.3 55.5 N.A. N.A. N.A. 31.6 36.5
Protein Similarity: 100 99.7 59.1 77.7 N.A. 94.8 58.5 N.A. N.A. N.A. 64.5 64.8 N.A. N.A. N.A. 42.5 49.8
P-Site Identity: 100 100 6.6 86.6 N.A. 93.3 6.6 N.A. N.A. N.A. 0 6.6 N.A. N.A. N.A. 6.6 0
P-Site Similarity: 100 100 13.3 86.6 N.A. 93.3 13.3 N.A. N.A. N.A. 13.3 13.3 N.A. N.A. N.A. 13.3 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 0 40 40 40 10 10 20 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 10 0 0 10 0 0 0 0 0 0 % C
% Asp: 10 0 10 0 0 0 0 0 0 10 30 0 0 0 0 % D
% Glu: 0 40 0 40 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 10 0 0 10 0 0 0 0 0 0 0 10 20 30 % F
% Gly: 0 0 40 0 0 0 0 10 20 40 40 0 0 0 40 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 40 0 0 % H
% Ile: 0 0 0 0 0 0 10 30 0 10 0 10 10 0 0 % I
% Lys: 0 10 10 30 0 0 0 0 0 0 10 0 0 0 0 % K
% Leu: 0 0 0 0 10 30 0 0 0 0 0 0 0 0 0 % L
% Met: 30 0 0 10 30 0 0 0 10 0 0 0 0 0 0 % M
% Asn: 40 0 0 10 0 0 0 10 30 0 0 0 0 10 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 10 70 40 0 0 % P
% Gln: 0 0 0 0 0 10 30 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 10 10 0 0 10 0 0 0 0 0 0 10 % R
% Ser: 10 30 20 0 0 0 10 30 10 10 0 10 0 50 10 % S
% Thr: 10 0 0 0 0 0 0 0 10 0 10 0 0 0 10 % T
% Val: 0 0 0 0 0 0 10 0 0 10 0 0 0 0 0 % V
% Trp: 0 0 10 0 0 10 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _